Referral Criteria for Prostate Cancer

The NKI Center for Early Diagnostics focuses on personalized risk stratification for early diagnosis and follow-up examinations. This reduces unnecessary prostate biopsies, diagnoses, and over-treatment. General practitioners and specialists can refer men with an elevated risk of prostate cancer to us. The following guidelines can be used for this purpose:

1. Asymptomatic men with an elevated serum PSA and a minimum life expectancy of >10 years. Men with moderately elevated serum PSA (PSA <10ng/ml) should preferably be referred only if, in two separate measurements with a 6-week interval, the PSA is elevated.
2. Men who are at increased risk of prostate cancer based on a family history, African descent, and/or BRCA1/2 mutation.
3. Symptomatic men (urinary symptoms) with an elevated serum PSA. These men should be referred to our Center if, in two separate measurements with a 6-week interval, the PSA is elevated.

At the NKI Center for Early Diagnostics we do not examine men with urinary symptoms due to benign prostatic hyperplasia. Please refer to the NHG guidelines. Referral to our Center is arranged via Zorgdomein, Antoni van Leeuwenhoek Centrum voor Vroegdiagnostiek.